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Anti-PKC gamma Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Protein kinase C gamma type |
Synonyms: | PKC gamma, PKCC, PKCG, PRKCG, Protein kinase C gamma type, protein kinase C, gamma, SCA14 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PKC gamma |
Uniprot ID: | P63318 |
Isotype: | lgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 78 kDa / 80 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 400 | brain, cerebellum |
Background
Calcium-activated, phospholipid- and diacylglycerol (DAG)-dependent serine/threonine-protein kinase that plays diverse roles in neuronal cells and eye tissues, such as regulation of the neuronal receptors GRIA4/GLUR4 and GRIN1/NMDAR1, modulation of receptors and neuronal functions related to sensitivity to opiates, pain and alcohol, mediation of synaptic function and cell survival after ischemia, and inhibition of gap junction activity after oxidative stress. Binds and phosphorylates GRIA4/GLUR4 glutamate receptor and regulates its function by increasing plasma membrane-associated GRIA4 expression.
Images
| WB analysis of PRKCG (GB115548). |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
