Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PLA2G1B rabbit polyclonal |
Gene Name: | Phospholipase A2 |
Synonyms: | Group IB phospholipase A2, PLA2, PLA2A, PLA2G1B, PPLA2, Phosphatidylcholine 2-acylhydrolase 1B, PLA2-Ib |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PLA2G1B |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 16 kDa |
Observed MW. | 16 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 600 | pancreas |
Background
This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.
Images
Western blot analysis of PLA2G1B (GB113673) at dilution of 1: 600 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |