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Anti-PMCA1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R & R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Plasma membrane calcium-transporting ATPase 1 |
Synonyms: | Plasma membrane calcium ATPase isoform 1, PMCA1, ATP2B1, Plasma membrane calcium pump isoform 1 |
Immunogen: | Recombinant protein corresponding to Mouse PMCA1 |
Uniprot ID: | G5E829 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. / Observed MW. | 135 kDa / 180-245 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 500-1: 1000 | cerebral cortex, cerebellum, hippocampus |
IHC/IF | Rat | 1: 500-1: 2000 | small intestine, colon |
Background
The calcium pump of the plasma membrane (PMCA ATPase) pumps calcium from the cytosol to the extracellular space. This membrane-bound enzyme is related to a number of other ATPases including the sarcoplasmic and endoplasmic reticulum calcium (SERCA) ATPase and the sodium/potassium pump. Studies indicate that there are four known isoforms of the PMCA ATPase which are encoded by a multigene family.
Images
| Western blot analysis of PMCA1 (GB111922) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat small intestine using PMCA1 (GB111922) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat duodenum using PMCA1 (GB111922) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded rat colon using PMCA1 (GB111922) at dilution of 1: 1000 |
| Immunofluorescent analysis of paraffin embedded rat colon using PMCA1 (GB111922) at dilution of 1: 500 |
| Immunofluorescent analysis of paraffin embedded rat bladder using PMCA1 (GB111922) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
