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Anti-POLD3 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | POLD3 rabbit polyclonal antibody |
Gene Name: | DNA polymerase delta subunit 3 |
Synonyms: | DNA polymerase delta subunit p66, Pold3, KIAA0039, Pol delta C subunit (p66), PPP1R128, P68 , P66, Protein phosphatase 1 |
Immunogen: | Recombinantproteincorrespondingto Mouse POLD3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Uniprot ID: | Q9EQ28 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 400-1: 1200 | testis |
Background
In DNA replication, exonucleases are involved in the processing of Okazaki fragments, whereas in DNA repair, they function to excise damaged DNA fragments and correct recombinational mismatches. These exonucleases include the family of DNA polymerases, namely DNA pol alpha, beta, delta and epsilon. DNA pol delta and DNA pol epsilon are multisubunit enzymes, with DNA pol delta consisting of two subunits which interact with the sliding DNA clamp protein PCNA.
Images
| Immunohistochemistry of paraffin embedded mouse testis using DNApoldelta3 (GB111683) at dilution of 1:650 (300x lens) |
| Immunohistochemistry of paraffin embedded rat testis using DNApoldelta3 (GB111683) at dilution of 1:1000 (300x lens) |
| Immunofluorescence of paraffin embedded mouse testis using DNApoldelta3 (GB111683) at dilution of 1:650 (400x lens) |
| Immunofluorescence of paraffin embedded rat testis using DNApoldelta3 (GB111683) at dilution of 1:1000 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
