Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PP1C gamma rabbit polyclonal antibody |
Gene Name: | Serine/threonine-protein phosphatase PP1-gamma catalytic subunit |
Synonyms: | Ppp1cc, PPP1CC, PP-1G, PP1C, PPP1G, Protein phosphatase 1 catalytic subunit gamma, PP1C-γ |
Immunogen: | Recombinant protein corresponding to Mouse PP1C-γ |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 37 kDa |
Observed MW. | 37 kDa |
Uniprot ID: | P36873, P63087, P63088 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | liver, kidney, brain |
Background
Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca2+/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. PPP1CC has been shown to interact with PPP1R15A, SMARCB1, TLX1 and PPP1R9B.
Images
Western blot analysis of PP1G (GB11755) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |