Reactivity: | H,M,R & M |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Peroxisome proliferator-activated receptor gamma |
Synonyms: | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma, peroxisome proliferator activated receptor gamma,PPAR-gamma, Nuclear receptor subfamily 1 group C member 3, Pparg, Nr1c3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PPAR gamma |
Uniprot ID: | P37238 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Predicted MW. / Observed MW. | 58 kDa / 50-60 kDa |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | skeletal muscle, liver |
IHC/IF | Mouse | 1: 600-1: 1200 | brown adipose tissue, spleen |
Background
This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer.
Images
Western blot analysis of PPARGAMMA2 (GB112205) at dilution of 1: 500 | |
Immunofluorescence of paraffin embedded mouse brown adipose tissue using PPARG (GB112205) at dilution of 1: 600 (400x lens) | |
Immunofluorescence of paraffin embedded mouse spleen using PPARG (GB112205) at dilution of 1: 600 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |