Reactivity: | M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PPHLN1/Periphilin-1 rabbit polyclonal antibody |
Gene Name: | Periphilin-1 |
Synonyms: | Pphln1, Gastric cancer antigen Ga50, CDC7 Expression Repressor , CR, HSPC206, HSPC232 |
Immunogen: | Recombinant protein corresponding to Mouse PPHLN1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Uniprot ID: | Q8K2H1 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 500-1: 2000 | brain, skin, testis |
Background
The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation.
Images
Immunohistochemistry of paraffin embedded mouse brain using PPHLN (GB112022) at dilution of 1:700 (200x lens) | |
Immunofluorescence of paraffin embedded mouse skin using PPHLN (GB112022) at dilution of 1:650 (200x lens) | |
Immunofluorescence of paraffin embedded mouse brain using PPHLN (GB112022) at dilution of 1:650 (300x lens) | |
Immunofluorescence of paraffin embedded rat testis using PPHLN (GB112022) at dilution of 1:650 (250x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |