Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PRDM10 rabbit polyclonal |
Gene Name: | PR domain zinc finger protein 10 |
Synonyms: | KIAA1231, PFM7, PR domain containing 10, PRDM10, TRIS, Tristanin |
Immunogen: | Recombinant protein corresponding to Mouse PRDM10 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 134 kDa |
Observed MW. | 150 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human | 1: 800-1: 1500 | K562, 293T |
Background
PRDM10 is a member of PRDM family, which contains a PR(PRDI-BF1 and RIZ homology) domain, and PRDM is also a subgroup of PR/SET transcription factor family for its PR domain is similar to the catalytic motif of the SET domain of histone methyltransferase(HMTase). Thus PRDM is suggested involve in the regulation of genome expression and chromatin remodeling. PRDM10 shares characteristics with the PR/SET faimly and clusters of zinc fingers DNA binding motifs. It's postualated PRDM10 has an essential role in regulating gene expression and tissue differentiation and a gene repressor. It may play a role in the pathogenesis of gangliosidosis.
Images
Western blot analysis of PRDM10 (GB113452) at dilution of 1: 1500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |