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Anti-PRKAR2B Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | cAMP-dependent protein kinase type II-beta regulatory subunit |
Synonyms: | Prkar2b, RATDNA, Protein kinase cAMP dependent regulatory type II beta, Pkarb2, H RG363E19.2, RIIbeta |
Immunogen: | Recombinant protein corresponding to Mouse PRKAR2B |
Uniprot ID: | P31324 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 46 kDa / 46 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | brain, fat |
Background
cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits.
Images
| Western blot analysis of PRKAR2B (GB111720) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
