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Anti-PRPH2/RDS Rabbit pAb (100 μl)
| Reactivity: | M,R & M,R |
| Applications: | WB & IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PRPH2/RDS rabbit polyclonal |
Gene Name: | Peripherin-2 |
Synonyms: | AOFMD, AVMD, Peripherin2, PRPH, PRPH2, rd2, RDS, RP7, Tetraspanin 22, Tspan 22, TSPAN22 |
Immunogen: | Recombinant protein corresponding to Mouse PRPH2/RDS |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Predicted MW. | 39 kDa |
Observed MW. | 39 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 3000 | eye |
IHC | Mouse, Rat | 1: 2000-1: 4000 | eyeball |
Background
Peripherin-2 (PRPH2), also known as retinal degeneration slow protein (RDS), is a photoreceptor-specific tetraspanin protein implicated in outer segment disk morphogenesis. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. Mutations in peripherin-2 are responsible for various retinal degenerative diseases including autosomal dominant retinitis pigmentosa (ADRP).
Images
| Western blot analysis of PRPH2 (GB113587) at dilution of 1: 3000 |
| Immunohistochemistry analysis of paraffin-embedded mouse eyeball using PRPH2 (GB113587) at dilution of 1: 4000 |
| Immunohistochemistry analysis of paraffin-embedded rat eyeball using PRPH2 (GB113587) at dilution of 1: 4000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
