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Anti-PRR14 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PRR14 rabbit polyclonal |
Gene Name: | Proline-rich protein 14 |
Synonyms: | proline rich 14, PRR14 |
Immunogen: | Recombinant protein corresponding to Mouse PRR14 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 1600-1: 3200 | brain |
Background
PRR14 (proline-rich protein 14) is a 585-amino acid protein with a calculated molecular weight of 64 kDa. This protein functions to tether heterochromatin to the nuclear periphery during interphase, through associations with heterochromatin protein 1 (HP1) and the nuclear lamina. After disassembly early in mitosis, PRR14 reassembles in two steps, first binding to anaphase chromosomes through HP1, followed by association with the nuclear lamina in telophase. PRR14 may thereby play a role in specifying HP1-bound heterochromatin for reattachment to the nuclear lamina at mitotic exit.
Images
| Immunohistochemistry analysis of paraffin-embedded mouse brain using PRR14 (GB113472) at dilution of 1: 3200 |
| Immunohistochemistry analysis of paraffin-embedded rat brain using PRR14 (GB113472) at dilution of 1: 3200 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
