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Anti-Presenilin 1 / PS-1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Presenilin 1 rabbit polyclonal antibody |
Gene Name: | Presenilin-1 |
Synonyms: | PSEN1, Psen1, Ad3h, PS-1, PS1, S182, AD3, FAD, presenilin 1, ACNINV3 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Presenilin 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 53 kDa |
Observed MW. | 22 kDa |
Uniprot ID: | P49768, P49769, P97887 |
Product Usage Information
| Applications | Species | Dilution | Positive Tissue |
| WB | Human, Mouse, Rat | 1: 1000-1: 1500 | brain, liver, spleen |
Background
Presenilin-1 is one of the four core proteins in the gamma secretase complex, which is considered to play an important role in generation of amyloid beta (Aβ) from amyloid precursor protein (APP). Accumulation of amyloid beta is associated with the onset of Alzheimer's disease.
Images
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Western blot analysis of Presenilin1 (GB11779) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
