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| Reactivity: | H,M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PSAP rabbit polyclonal antibody |
Gene Name: | Prosaposin |
Synonyms: | Saposin-A, Saposin-B-Val, Saposin-B, Cerebroside sulfate activator, SAP-1, SAP-2, Saposin-C, Saposin-D, PSAP, GLBA, SAP1 |
Immunogen: | Recombinant protein corresponding to Human PSAP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Secreted, Cytoplasm |
Uniprot ID: | P07602, Q61207, P10960 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1:750-1:1500 | brain, kidney, liver, lung, prostate, testis |
Background
This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups.
Images
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Immunohistochemistry of paraffin embedded human prostate using PSAP (GB111172) at dilution of 1:750 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using PSAP (GB111172) at dilution of 1:1500 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using PSAP (GB111172) at dilution of 1:1500 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using PSAP (GB111172) at dilution of 1:1500 (400x lens) |
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Immunofluorescence of paraffin embedded human prostate using PSAP (GB111172) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded mouse brain using PSAP (GB111172) at dilution of 1:1400 (400x lens) |
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Immunofluorescent analysis of paraffin-embedded human prostate using PSAP (GB111172) at dilution of 1: 750 |
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Immunofluorescence of paraffin embedded mouse testis using PSAP (GB111172) at dilution of 1:1400 (400x lens) |
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Immunofluorescence of paraffin embedded rat kidney using PSAP (GB111172) at dilution of 1:1400 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
