Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PSD93 rabbit polyclonal antibody |
Gene Name: | Disks large homolog 2 |
Synonyms: | Channel-associated protein of synapse-110, Chapsyn-110, Postsynaptic density protein PSD-93, DLG2, channel-associated protein of synapses, Chapsyn-1, discs large 2, discs large homolog 2, discs, Post Synaptic Density 93, Postsynaptic density protein PSD-9 |
Immunogen: | Recombinant protein corresponding to Mouse PSD93 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 98 kDa |
Observed MW. | 110 kDa |
Uniprot ID: | Q15700 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, SH-SY5Y, Jurkat |
Background
Chapsyn-110, is a part of the membrane-associated putative guanylate kinase (MAGUK) family. It binds directly to the NMDA receptor, and Shaker K+ channel subunits, and is 70-80% identical to PSD-95/SAP90 and SAP97. It associated tightly with the postsynaptic density I brain, and mediates the clustering of both NMDA recpetors and K+ channels in heterologous cells. The encoded protein forms a heterodimer with PSD-95 that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
Images
Western blot analysis of PSD93 (GB111562) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |