Reactivity: | M,R |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | PSIP1/LEDGF rabbit polyclonal |
Gene Name: | PC4 and SFRS1-interacting protein |
Synonyms: | CLL associated antigen KW 7, DFS 70, DFS70, LEDGF, p52, p75, PAIP, PSIP1, PSIP2, Lens epithelium-derived growth factor, mLEDGF |
Immunogen: | Recombinant protein corresponding to Mouse PSIP1/LEDGF |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Mouse, Rat | 1: 1500-1: 3000 | testis |
Background
Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration.. This protein has 2 isoforms produced by alternative splicing.
Images
Immunohistochemistry analysis of paraffin-embedded mouse testis using PSIP1 (GB113471) at dilution of 1: 3000 | |
Immunohistochemistry analysis of paraffin-embedded rat testis using PSIP1 (GB113471) at dilution of 1: 3000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |