Anti-PTBP1 Rabbit pAb (100 μl)

Anti-PTBP1 Rabbit pAb (100 μl)

Brand: ServiceBio
Cat. #: GB111960-100
Availability: In Stock
$259.00
-+
Reactivity: H,M,R & M,R    
Applications: WB & IHC/IF    
Host Species: Rabbit    
Clonality: Polyclonal    
Full Name:

PTBP1 rabbit polyclonal antibody

Gene Name:

Polypyrimidine tract-binding protein 1

Synonyms:

PTB, Heterogeneous nuclear ribonucleoprotein I, hnRNP I, Ptbp1, Ptb, HNRNPI, HNRPI, PTBP1

Immunogen:

KLH conjugated Synthetic peptide corresponding to Mouse PTBP1

Isotype:

IgG

Purity:

Affinity purification

Subcellular location:

Nucleus

Predicted MW.

56 kDa

Observed MW.

56 kDa

Uniprot ID:

P26599, P17225, Q00438




Product Usage Information

Applications

Species

Dilution

Positive Sample

WB

Human, Mouse, Rat

1: 500-1: 1000

Jurkat, A549, K562, C2C12, L6

IHC/IF

Mouse, Rat

1: 500-1: 1000

heart, kidney, lung




Background

Polypyrimidine tract-binding protein (PTBP1), also known as heterogeneous nuclear ribonucleoprotein type I (hnRNP I), is a nuclear protein that binds pre-mRNAs in specific regions of the hnRNA-protein complexes sensitive to micrococcal nuclease. It involves in pre-mRNA splicing and the regulation of alternative splicing events. PTBP1 promotes RNA looping when bound to two separate polypyrimidine tracts in the same pre-mRNA, and promotes the binding of U2 snRNP to pre-mRNA.




Images

Western blot analysis of PTBP1 (GB111960) at dilution of 1: 500

Immunohistochemistry of paraffin embedded mouse heart using PTBP1 (GB111960) at dilution of 1: 500 (400x lens)
Immunohistochemistry of paraffin embedded mouse kidney using PTBP1 (GB111960) at dilution of 1: 500 (400x lens)
Immunohistochemistry of paraffin embedded mouse lung using PTBP1 (GB111960) at dilution of 1: 500 (400x lens)

Immunohistochemistry of paraffin embedded rat heart using PTBP1 (GB111960) at dilution of 1: 500 (400x lens)

Immunohistochemistry of paraffin embedded rat lung using PTBP1 (GB111960) at dilution of 1: 500 (400x lens)




Storage

StorageStore at -20°C for one year. Avoid repeated freeze/thaw cycles.
Storage BufferPBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol.


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