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Anti-PTGIS/PGIS Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PTGIS/PGIS rabbit polyclonal antibody |
Gene Name: | Prostacyclin synthase |
Synonyms: | Hydroperoxy icosatetraenoate dehydratase, Prostaglandin I2 synthase, Cyp8, CYP8A1, PGIS, EC 5.3.99.4, PTGIS |
Immunogen: | Recombinant protein corresponding to Mouse PTGIS/PGIS |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 57 kDa |
Observed MW. | 55 kDa |
reactivity （External validation） | Human |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Mouse, Rat | 1: 500-1: 1000 | lung, stomach |
Background
CYP8A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation.
Images
| Western blot analysis of PTGIS (GB111714) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
