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Anti-PTP-H1 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PTP-H1 rabbit polyclonal antibody |
Gene Name: | Tyrosine-protein phosphatase non-receptor type 3 |
Synonyms: | Ptpn3, protein tyrosine phosphatase H1, PTPH1, protein tyrosine phosphatase non-receptor type 3 |
Immunogen: | Recombinant protein corresponding to Mouse PTP-H1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cytoplasm |
Uniprot ID: | A2ALK8 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 700-1: 1400 | small intestine, testis |
Background
Phosphorylation of receptors by protein kinases is a process that can be reversed by a group of enzymes called protein phosphatases. Coordinated control of kinases and phosphatases provides the cell with the capacity to rapidly switch between phosphorylated and dephosphorylated protein states in dynamic response to environmental stimuli. Activation of critical enzymes by kinase phosphorylation alone is not enough to provide adequate regulation - it is the combination with phosphatase dephosphorylation that effectively creates on/off switches to control cellular events.
Images
| Immunohistochemistry of paraffin embedded mouse small intestine using PTPN3 (GB111774) at dilution of 1:700 (300x lens) |
| Immunohistochemistry of paraffin embedded mouse testis using PTPN3 (GB111774) at dilution of 1:700 (300x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
