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Anti-PVRL1/NECTIN1 Rabbit pAb (100 μl)
| Reactivity: | H |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | PVRL1/NECTIN1 rabbit polyclonal antibody |
Gene Name: | Nectin-1 |
Synonyms: | Herpes virus entry mediator C, Herpesvirus entry mediator C, HveC, Nectin cell adhesion molecule 1, Poliovirus receptor-related protein 1, CD111, CLPED1, ED4, HIgR, OFC7, OROFACIAL CLEFT 7 |
Immunogen: | Recombinant protein corresponding to Mouse PVRL1/NECTIN1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 57 kDa |
Observed MW. | 57 kDa |
Uniprot ID: | Q15223 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human | 1: 500-1: 1000 | HeLa, HepG2, HaCaT, SK-BR-3 |
Background
This gene encodes an adhesion protein that plays a role in the organization of adherens junctions and tight junctions in epithelial and endothelial cells. The protein is a calcium(2+)-independent cell-cell adhesion molecule that belongs to the immunoglobulin superfamily and has 3 extracellular immunoglobulin-like loops, a single transmembrane domain, and a cytoplasmic region. This protein acts as a receptor for glycoprotein D of herpes simplex viruses 1 and 2, and pseudorabies virus and mediates viral entry into epithelial and neuronal cells. Mutations in this gene cause cleft lip and palate/ectodermal dysplasia 1 syndrome as well as non-syndromic cleft lip with or without cleft palate.
Images
| Western blot analysis of Nectin1 (GB111715) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
