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Anti-Paxillin Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Paxillin rabbit polyclonal antibody |
Gene Name: | Paxillin |
Synonyms: | Pxn, PXN, entrez:5829, paxillin |
Immunogen: | Recombinant protein corresponding to Mouse Paxillin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 65 kDa |
Observed MW. | 72 kDa |
Uniprot ID: | P49023, Q8VI36, Q66H76 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 20000-1: 50000 | spleen, lung, testis |
Background
Paxillin is a protein encoded by the PXN gene. Paxillin is a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Mutations in PXN as well as abnormal expression of paxillin protein has been implicated in the progression of various cancers. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.
Images
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Western blot analysis of Paxillin (GB11831) at dilution of 1: 20000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
