Reactivity: | M,R & M,R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Peroxiredoxin 4 rabbit polyclonal |
Gene Name: | Peroxiredoxin-4 |
Synonyms: | Antioxidant enzyme AOE372, AOE37 2, Peroxiredoxin IV, PRDX4, PRX 4, Prx-IV, Thioredoxin peroxidase AO372 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Peroxiredoxin 4 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Endoplasmic reticulum |
Predicted MW. | 31 kDa |
Observed MW. | 31 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 300-1: 600 | testis, liver, pancreas |
IHC | Mouse, Rat | 1: 2000-1: 4000 | placenta, testis |
Background
PRDX4 (Peroxiredoxin-4) is also named as AOE37-2, Prx-IV and belongs to the AhpC/TSA family. PRDX4 is associated with acrosome formation during rat spermatogenesis and has a protective role in the male reproductive tract, because the phenotype of mice lacking this isoform includes testicular atrophy and increased sperm DNA damage . It is initially synthesized as a membrane-binding 31-kDa protein and processed into a 27-kDa secretory form and is discarded with the residual bodies . PRDX4 is a pentamer of dimers . This antibody is specific to PRDX4.
Images
Western blot analysis of PRDX4 (GB113672) at dilution of 1: 600 | |
Immunohistochemistry analysis of paraffin-embedded mouse placenta using PRDX4 (GB113672) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded mouse testis using PRDX4 (GB113672) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded rat testis using PRDX4 (GB113672) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |