Reactivity: | H |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Tyrosine-protein kinase JAK1 |
Synonyms: | JAK-1, JAK1, JAK1A, JAK1B, Janus kinase 1, JTK3, Tyrosine protein kinase JAK1, P-JAK1 |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human JAK1(Tyr1034/Tyr1035) |
Uniprot ID: | P23458 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 133 kDa / 130 kDa |
Product Usage Information
WB | Human | 1: 300-1: 600 | HeLa |
Background
Janus kinase 1(JAK1), is a member of a class of protein-tyrosine kinases (PTK) characterized by the presence of a second phosphotransferase-related domain immediately N-terminal to the PTK domain. JAK1 is essential for signaling for certain type I and type II cytokines. JAK1 plays a critical role in initiating responses to multiple major cytokine receptor families. Expression of JAK1 in cancer cells enables individual cells to contract, potentially allowing them to escape their tumor and metastasize to other parts of the body.
Images
Western blot analysis of Phospho-JAK1(Tyr1034/Tyr1035) (GB114584) at dilution of 1: 300. |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |