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Anti-Phospho-JAK2 (Y1007+Y1008) Rabbit pAb (100 μl)
| Reactivity: | H,M,R & H |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Tyrosine-protein kinase JAK2 |
Synonyms: | AK2, JTK10, THCYT3, Janus kinase 2, MAX2, P-JAK2 |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human JAK2(Tyr1007+Tyr1008) |
Uniprot ID: | O60674 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. / Observed MW. | 131 kDa / 125 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 600 | C6, NIH/3T3 |
IHC/IF | Human | 1: 400-1: 800 | cervical carcinoma, lung adenocarcinoma |
Background
This gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.
Images
| Western blot analysis of Phospho-JAK2(Tyr1007+Tyr1008) (GB114585) at dilution of 1: 300 |
| Western blot analysis of Phospho-JAK2(Tyr1007+Tyr1008) (GB114585) at dilution of 1: 300 |
| Immunohistochemistry analysis of paraffin embedded human cervical carcinoma using Phospho-JAK2(Y1007+Y1008) (GB114585) at dilution of 1: 650 The figure left was treated with non-phospho-blocking peptide, the figure right was treated with phospho-blocking peptide |
| Immunohistochemistry analysis of paraffin embedded human lung adenocarcinoma using Phospho-JAK2(Y1007+Y1008) (GB114585) at dilution of 1: 650 The figure left was treated with non-phospho-blocking peptide, the figure right was treated with phospho-blocking peptide |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
