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Anti-Phospho-PTEN (S380) Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN |
Synonyms: | 10q23del, Bannayan Zonana syndrome, BC005821, BZS, ITGA 2, MGC11227, MHAM, MMAC1, Multiple hamartoma (Cowden syndrome), phosphatase and tensin homolog, PTEN, PTEN1, TEP1, P-PETN |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human PTEN(S380) |
Uniprot ID: | P60484 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 47/64/20 kDa / 54 kDa |
Product Usage Information
WB | Human, Mouse, Rat | 1: 300-1: 600 | HeLa, NIH/3T3, C6, 293 |
Background
PTEN(Phosphatase and tensin homolog) is also named as MMAC1, TEP1 and it modulates cell cycle progression and cell survival (blockage) through down-regulating the positive cell cycle-regulator (cycle D1) by its phosphatase activity and up-regulating the negative cell cycle regulator p21 (by its lipid phosphatase activity). PTEN is an important tumor suppressor whose inactivation frequency in cancers is ranked second after p53 tumor suppressor inactivation.
Images
| Western blot analysis of Phospho-PTEN(S380) (GB114583) at dilution of 1: 300. The figure above was untreated, the figure bleow was treated with lambda phosphatase. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
