Reactivity: | M |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Phospho-p38 (T180/Y182) rabbit polyclonal |
Gene Name: | Mitogen-activated protein kinase 14 |
Synonyms: | CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A, SAPK2a, MAX-interacting protein 2, MAP kinase MXI2, CSAID-binding protein, MAP kinase 14, MAPK14, p38, p38 MAPK, P-P38 |
Immunogen: | KLH conjugated Synthetic phosphopeptide corresponding to Human p38 (T180/Y182) |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 41 kDa |
Observed MW. | 43 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | 293, PC12, C6, NIH/3T3 |
Background
MAPK14(mitogen-activated protein kinase 14) is also named as SAPK2A, p38MAPK, CSBP1, RK, p38, EXIP, Mxi2, CSBP2, PRKM14, PRKM15, CSPB1, p38ALPHA and belongs to the MAP kinase subfamily. MAPK14-signaling is a central pathway for the integration of instructive signals in dendritic cells for T(H)17 differentiation and inflammation. It plays an important role in the regulation of hematopoietic stem cellself-renewal in vitro and inhibition of MAPK14 activation with a small molecule inhibitor may represent a novel approach to promote ex vivo expansion of hematopoietic stem cell. This protein has 4 isoforms produced by alternative splicing.
Images
Western blot analysis of phospho-p38 (T180/Y182) (GB113380) at dilution of 1: 1000 Lane1: 293 untreated Lane2: 293 treated with UV(30min) Lane3: PC12 untreated Lane4: PC12 treated with UV(30min); Lane5: C6 untreated Lane6: C6 treated with UV(30min) Lane7: NIH/3T3 untreated Lane8: NIH/3T3 treated with UV(30min) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |