Your shopping cart is empty!
Anti-Phosphomevalonate kinase Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Phosphomevalonate kinase rabbit polyclonal |
Gene Name: | Phosphomevalonate kinase |
Synonyms: | hPMK, HUMPMKI, PMK, PMKA, PMKASE, PMKI, PMVK |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse PMVK |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Peroxisome |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 1000-1: 4000 | kidney |
IF | Human | 1: 2000-1: 4000 | kidney |
Background
This gene encodes a peroxisomal enzyme that is a member of the galactokinase, homoserine kinase, mevalonate kinase, and phosphomevalonate kinase (GHMP) family of ATP-dependent enzymes. The encoded protein catalyzes the conversion of mevalonate 5-phosphate to mevalonate 5-diphosphate, which is the fifth step in the mevalonate pathway of isoprenoid biosynthesis. Mutations in this gene are linked to certain types of porokeratosis including disseminated superficial porokeratosis. Alternative splicing results in multiple transcript variants.
Images
 |
Immunohistochemistry analysis of paraffin-embedded human kidney using PMVK (GB11352) at dilution of 1: 2000. |
 |
Immunohistochemistry analysis of paraffin-embedded human kidney using PMVK (GB11352) at dilution of 1: 4000. |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
