Reactivity: | M,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Plexin-C1 |
Synonyms: | Virus-encoded semaphorin protein receptor, CD232, Plxnc1, Vespr |
Immunogen: | Recombinant protein corresponding to Mouse Plxnc1 |
Uniprot ID: | Q9QZC2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Membrane |
Predicted MW. / Observed MW. | 176 kDa / 176 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | NIH-3T3, C6, L929, PC12 |
IHC/IF | Mouse, Rat | 1: 650-1: 6500 | embryonic mouse, heart |
Background
This gene encodes a member of the plexin family. Plexins are transmembrane receptors for semaphorins, a large family of proteins that regulate axon guidance, cell motility and migration, and the immune response. The encoded protein and its ligand regulate melanocyte adhesion, and viral semaphorins may modulate the immune response by binding to this receptor. The encoded protein may be a tumor suppressor protein for melanoma.
Images
Western blot analysis of Plxnc1 (GB112229) at dilution of 1: 1000 | |
Immunofluorescence analysis of paraffin embedded mouse embryonic mouse using PLXNC1 (GB112229) at dilution of 1: 650 | |
Immunofluorescence analysis of paraffin embedded mouse heart using PLXNC1 (GB112229) at dilution of 1: 650 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |