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Anti-Profilin 1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Profilin 1 rabbit polyclonal antibody |
Gene Name: | Profilin-1 |
Synonyms: | Pfn1, PFN1, ALS18, Profilin 1 |
Immunogen: | Recombinant protein corresponding to Mouse Profilin 1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 15 kDa |
Observed MW. | 15 kDa |
Uniprot ID: | P07737, P62962, P62963 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1:500-1:1000 | testis, skin, lung |
Background
Profilin-1 is a protein encoded by the PFN1 gene. The protein is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome. Mutations in this gene may be a rare cause of amyotrophic lateral sclerosis, also called Lou Gehrig's disease.
Images
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Western blot analysis of Profilin (GB11787) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
