Reactivity: | H & H,M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Monoclonal |
Gene Name: | Progesterone receptor |
Gene ID: | 5241 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Human Progesterone receptor |
Uniprot ID: | P06401 |
Source: | Monoclonal, Rabbit IgG1, Kappa |
Concentration: | 1mg/ml |
Purity: | Recombinant Expression and Affinity purified |
Product Usage Information
WB | Human | 1: 500-1: 1000 | T-47D |
IHC/IF | Human, Mouse, Rat | 1:200-1:400 | endometrial cancer, uterus |
Background
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This gene uses two distinct promotors and translation start sites in the first exon to produce several transcript variants, both protein coding and non-protein coding. Two of the isoforms (A and B) are identical except for an additional 165 amino acids found in the N-terminus of isoform B and mediate their own response genes and physiologic effects with little overlap.
Images
Western blot analysis of Progesterone receptor (GB14169) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin embedded Human endometrial cancer using Progesterone receptor (GB14169) at dilution of 1: 200 | |
Immunohistochemistry analysis of paraffin embedded Mouse uterus using Progesterone receptor (GB14169) at dilution of 1: 200 | |
Immunohistochemistry analysis of paraffin embedded Rat breast using Progesterone receptor (GB14169) at dilution of 1: 200 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |