Your shopping cart is empty!
Anti-Prohibitin Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Prohibitin rabbit polyclonal antibody |
Gene Name: | Prohibitin |
Synonyms: | B-cell receptor-associated protein 32, C-BAP 32, Phb, PHB, HEL-215, HEL-S-54e, PHB1, Prohibitin |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Prohibitin |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 30 kDa |
Observed MW. | 30 kDa |
Uniprot ID: | P35232, P67778, P67779 |
Images
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | heart, brain |
Background
Prohibitin, also known as PHB, a member of the Band-7 family of proteins, is widely distributed in bacteria, plants, yeast, protozoa and mammals and is important in cell proliferation, differentiation and apoptosis . This protein localizes to the inner membrane of mitochondria, where it acts as a chaperone protein, and is also found in the nucleus, where it negatively regulates transcription. Recent study confirmed that the expression and distribution of PHB, which is a nuclear matrix protein, affect the apoptosis of HaCaT cells and its co-localization with specific gene products connected with cell apoptosis .
Images
| Western blot analysis of Prohibitin (GB111045) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
