Your shopping cart is empty!
Anti-Prostaglandin D2 Receptor Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Prostaglandin D2 Receptor rabbit polyclonal |
Gene Name: | Prostaglandin D2 receptor |
Synonyms: | PGD receptor, PGD2 receptor, Prostanoid DP receptor, Ptgdr, ASRT1, AS1, Prostaglandin D2 receptor , DP |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Prostaglandin D2 Receptor |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 40 kDa |
Observed MW. | 50 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 1000-1: 2000 | lung, kidney, small intestine |
Background
Receptor for prostaglandin D2 (PGD2). The activity of this receptor is mainly mediated by G(s) proteins that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP. A mobilization of calcium is also observed, but without formation of inositol 1,4,5-trisphosphate . Involved in PLA2G3-dependent maturation of mast cells. PLA2G3 is secreted by immature mast cells and acts on nearby fibroblasts upstream to PTDGS to synthesize PGD2, which in turn promotes mast cell maturation and degranulation via PTGDR.
Images
 | Western blot analysis of PD2R (GB113005) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
