Reactivity: | H,M,R & R |
Applications: | WB & IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | Proteasome 20S beta 7/PSMB7 rabbit polyclonal |
Gene Name: | Proteasome subunit beta type-7 |
Synonyms: | Macropain chain Z, Multicatalytic endopeptidase complex chain Z, Proteasome subunit Z, Psmb7, Mmc14, PUP1 |
Immunogen: | Recombinant protein corresponding to Mouse PSMB7 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 30 kDa |
Observed MW. | 27 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 800-1: 2000 | testis, liver, kidney, prostate |
IHC | Rat | 1: 2000-1: 4000 | brain |
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.
Images
Western blot analysis of PSMB7 (GB113453) at dilution of 1: 2000 | |
Western blot analysis of PSMB7 (GB113453) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded rat brain using PSMB7 (GB113453) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |