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Anti-Proteasome 26S S2/PSMD2 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | Proteasome 26S S2/PSMD2 rabbit polyclonal |
Gene Name: | 26S proteasome non-ATPase regulatory subunit 2 |
Synonyms: | 26S proteasome subunit p97, P97, Protein 55.11, PSMD2, Rpn1, S2, TRAP2, 26S proteasome regulatory subunit S2, 26S proteasome regulatory subunit RPN1 |
Immunogen: | Recombinant protein corresponding to Mouse PSMD2 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 100 kDa |
Observed MW. | 100 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Human, Mouse, Rat | 1: 1000-1: 2000 | skeletal muscle, liver |
Background
Tumor necrosis factor type 1 receptor-associated protein 2 (TRAP2), encoded by PSMD2 gene, is a non-ATPase regulatory subunit of the 26 proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. TRAP2 may also participate in the TNF signalling pathway since it interacts with the tumor necrosis factor type 1 receptor.
Images
 | Western blot analysis of PSMD2 (GB113525) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
