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Anti-RAB3GAP1 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RAB3GAP1 rabbit polyclonal antibody |
Gene Name: | Rab3 GTPase-activating protein catalytic subunit |
Synonyms: | RAB3 GTPase-activating protein 130 kDa subunit, Rab3-GAP p130, Rab3-GAP, Rab3gap1, Kiaa0066, WARBM1 |
Immunogen: | Recombinantproteincorresponding to Mouse RAB3GAP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 110 kDa |
Observed MW. | 130 kDa |
Uniprot ID: | Q15042, Q80UJ7, P69735 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse, Rat | 1: 500-1: 1000 | brain, kidney |
Background
RAB3GAP1 (RAB3 GTPase-activating protein 1) is the catalytic subunit of the heterodimeric enzyme RAB3GAP (RAB3GTPase-activating protein), a key regulator of the RAB3 cycle, which controls calcium-mediated exocytosis of neurotransmitters and hormones. Mutations in RAB3GAP1 cause Warburg Micro syndrome and Martsolf syndrome , phenotypically overlapping autosomal recessive conditions characterized by ocular and neurodevelopmental manifestations.
Images
| Western blot analysis of Rab3GAPp130 (GB111705) at dilution of 1: 500 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
