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| Reactivity: | H,M & M,R |
| Applications: | WB & IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RAP1 rabbit polyclonal antibody |
Gene Name: | Telomeric repeat-binding factor 2-interacting protein 1 |
Synonyms: | TERF2IP, DRIP5, RAP1, TERF2 interacting protein |
Immunogen: | Recombinant protein corresponding to Mouse RAP1 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Predicted MW. | 45 kDa |
Observed MW. | 46 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 500-1: 1000 | spleen, thymus |
IHC/IF | Mouse, Rat | 1: 500-1: 3000 | brain, lung |
Background
Telomeric repeat-binding factor 2-interacting protein 1 acts both as a regulator of telomere function and as a transcription regulator. it is involved in the regulation of telomere length and protection as a component of the shelterin complex (telosome). In contrast to other components of the shelterin complex, it is dispensible for telomere capping and does not participate in the protection of telomeres against non-homologous end-joining (NHEJ)-mediated repair. Instead, it is required to negatively regulate telomere recombination and is essential for repressing homology-directed repair (HDR), which can affect telomere length.
Images
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Western blot analysis of Rap1 (GB11608) at dilution of 1: 500 |
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Immunohistochemistry of paraffin embedded mouse lung using rap1 (GB11608) at dilution of 1: 2000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using rap1 (GB11608) at dilution of 1: 3000 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using rap1 (GB11608) at dilution of 1: 2000 (400x lens) |
 | Immunohistochemistry of paraffin embedded rat lung using rap1 (GB11608) at dilution of 1: 2000 (400x lens) |
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Immunofluorescence of paraffin embedded rat brain using rap1 (GB11608) at dilution of 1: 2000 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
