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Anti-RAPGEF5 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RAPGEF5 rabbit polyclonal antibody |
Gene Name: | Rap guanine nucleotide exchange factor 5 |
Synonyms: | Guanine nucleotide exchange factor for Rap1, M-Ras-regulated Rap GEF, Rapgef5, Mrgef, Kiaa0277, Gfr, Related to Epac, Rap guanine nucleotide exchange factor 5 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RAPGEF5 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus |
Uniprot ID: | Q8C0Q9, P83900 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 700-1: 1400 | brain, liver, spleen, testis |
Background
Members of the RAS subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as Repac, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
Images
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Immunohistochemistry of paraffin embedded mouse liver using RAPGEF5 (GB111597) at dilution of 1:700 (300x lens) |
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Immunohistochemistry of paraffin embedded mouse brain using RAPGEF5 (GB111597) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse testis using RAPGEF5 (GB111597) at dilution of 1:700 (400x lens) |
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Immunohistochemistry of paraffin embedded rat spleen using RAPGEF5 (GB111597) at dilution of 1:700 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
