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Anti-RASGRP3 Rabbit pAb (100 μl)
| Reactivity: | R & M,R & M,R |
| Applications: | WB & IHC & IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | RASGRP3 rabbit polyclonal |
Gene Name: | Ras guanyl-releasing protein 3 |
Synonyms: | RASGRP3, RASGRP3, GRP3, RAS guanyl releasing protein 3 |
Immunogen: | Recombinant protein corresponding to Human RASGRP3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane |
Predicted MW. | 78 kDa |
Observed MW. | 78 kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Rat | 1: 500-1: 1000 | liver, kidney |
IHC | Mouse, Rat | 1: 300-1: 1000 | brain |
IF | Mouse, Rat | 1: 150-1: 300 | brain |
Background
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RASGRP3, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation.
Images
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Western blot analysis of RASGRP3 (GB11934) at dilution of 1: 1000 Lane 1:Rat liver tissue lysate Lane 2: Rat kidney tissue lysate |
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Immunohistochemistry analysis of paraffin-embedded mouse brain using RASGRP3 (GB11934) at dilution of 1: 1000 |
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Immunohistochemistry analysis of paraffin-embedded rat brain using RASGRP3 (GB11934) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
