Reactivity: | H,M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | RASSF8 rabbit polyclonal antibody |
Gene Name: | Ras association domain-containing protein 8 |
Synonyms: | Carcinoma-associated protein HOJ-1 homolog, Rassf8, C12orf2, HoJ1, Ras association domain family 8 |
Immunogen: | Recombinant protein corresponding to Mouse RASSF8 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 48 kDa |
Observed MW. | 53 kDa |
Uniprot ID: | Q8CJ96 |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
WB | Mouse, Rat | 1: 250-1: 500 | liver, kidney |
Background
This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Images
Western blot analysis of RASSF8 (GB112390) at dilution of 1: 250 | |
Western blot analysis of RASSF8 (GB112390) at dilution of 1: 250 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |