Reactivity: | H |
Applications: | IHC |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | RBM14 rabbit polyclonal |
Gene Name: | RNA-binding protein 14 |
Synonyms: | COAA, Paraspeckle protein 2, PSP2, RBM14, RNA-binding motif protein 14, SIP, SYT interacting protein, SYTIP1, TMEM137 |
Immunogen: | Recombinant protein corresponding to Mouse RBM14 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC | Human | 1: 1000-1: 2000 | colon cancer, esophageal cancer, lung cancer, colon, placenta |
Background
This gene encodes a ribonucleoprotein that functions as a general nuclear coactivator, and an RNA splicing modulator. This protein contains two RNA recognition motifs (RRM) at the N-terminus, and multiple hexapeptide repeat domain at the C-terminus that interacts with thyroid hormone receptor-binding protein (TRBP), and is required for transcription activation. Alternatively spliced transcript variants encoding different isoforms (with opposing effects on transcription) have been described for this gene.
Images
Immunohistochemistry analysis of paraffin-embedded human colon cancer using RBM14 (GB113546) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded human esophageal cancer using RBM14 (GB113546) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded human lung cancer using RBM14 (GB113546) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded human colon using RBM14 (GB113546) at dilution of 1: 2000 | |
Immunohistochemistry analysis of paraffin-embedded human placenta using RBM14 (GB113546) at dilution of 1: 2000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |