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Anti-RBM24 Rabbit pAb (100 μl)
| Reactivity: | M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | RNA-binding protein 24 |
Synonyms: | NA binding motif protein 24, RNA binding protein 24, RNPC6 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RBM24 |
Uniprot ID: | D3Z4I3 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 25 kDa / 28 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 500-1: 1000 | liver |
Background
Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation . Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation . Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing . Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes.
Images
| Western blot analysis of RBM24 (GB115108) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
