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Anti-RBM38 Rabbit pAb (100 μl)
| Reactivity: | H,M,R |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | RNA-binding protein 38 |
Synonyms: | HSRNASEB, RNPC1, SEB4, SEB4B, SEB4D, ssDNA binding protein SEB4 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RBM38 |
Uniprot ID: | Q62176 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 25 kDa / 30 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 2000-1: 4000 | kidney |
Background
RNA-binding protein that specifically bind the 3'-UTR of CDKN1A transcripts, leading to maintain the stability of CDKN1A transcripts, thereby acting as a mediator of the p53/TP53 family to regulate CDKN1A. CDKN1A is a cyclin-dependent kinase inhibitor transcriptionally regulated by the p53/TP53 family to induce cell cycle arrest. Has the ability to induce cell cycle arrest in G1 and maintain the stability of CDKN1A transcripts induced by p53/TP53. Also acts as a mRNA splicing factor. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2 (By similarity). Plays a role in myogenic differentiation.
Images
| Western blot analysis of RBM38 (GB115250) at dilution of 1: 2000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
