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| Reactivity: | H |
| Applications: | IHC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Rho-related GTP-binding protein RhoU |
Synonyms: | WRCH-1, Ryu GTPase, CDC42-like GTPase 1, SB128, ARHU, CDC42L1, G28K, WRCH1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse RHOU |
Uniprot ID: | Q9EQT3 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cell membrane, Cell junction |
Product Usage Information
IHC/IF | Human | 1: 500-1: 1500 | stomach, colon |
Background
Acts upstream of PAK1 to regulate the actin cytoskeleton, adhesion turnover and increase cell migration. Stimulates quiescent cells to reenter the cell cycle. Has no detectable GTPase activity but its high intrinsic guanine nucleotide exchange activity suggests it is constitutively GTP-bound. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape.
Images
| Immunohistochemistry analysis of paraffin embedded human stomach using RHOU (GB115347) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded human colon using RHOU (GB115347) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
