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| Reactivity: | H,M |
| Applications: | WB |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Full Name: | ROR1 rabbit polyclonal antibody |
Gene Name: | Inactive tyrosine-protein kinase transmembrane receptor ROR1 |
Synonyms: | NTRKR1, ROR1, Neurotrophic tyrosine kinase, receptor-related 1, mROR1, dJ537F10.1 |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse ROR1 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. | 104kDa |
Observed MW. | 104kDa |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Mouse | 1: 300-1: 800 | heart |
Background
ROR1 is a member of the RTK family of orphan receptors related to muscle specific kinase and Trk neurotrophin receptors . ROR1 is primarily expressed by neural crest cells during embryogenesis. High expression of ROR1 is reported in many types of malignancies and is thought to be involved in tumor growth, apoptosis, and epithelial-mesenchymal transition . The human ROR1 gene encodes a 937-amino acid protein with an Ig-like domain, a cysteine-rich domain, a kringle domain, a tyrosine kinase domain and a proline-rich domain. The calculated molecular weight of ROR1 is 104 kDa, but ROR1 has multiple N-glycosylation sites that generate post-translationally modified ROR1 at 130 kDa.
Images
| Western blot analysis of ROR1 (GB113772) at dilution of 1: 800 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
| Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |
