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Anti-RRAGC Rabbit pAb (100 μl)
| Reactivity: | M,R & H,M |
| Applications: | IHC/IF & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Ras-related GTP-binding protein C |
Synonyms: | RagC, GTPase-interacting protein 2, TIB929, Rragc, TIB929, GTR2, RRAGC |
Immunogen: | Recombinant protein corresponding to Mouse RRAGC |
Uniprot ID: | Q99K70 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm, Nucleus |
Images
IHC/IF | Mouse, Rat | 1: 1000-1: 4000 | kidney, lung, testis |
ICC/IF | Human, Mouse | 1: 100-1: 400 | HeLa |
Background
RRAGC is a monomeric guanine nucleotide-binding protein, or G protein. By binding GTP or GDP, small G proteins act as molecular switches in numerous cell processes and signaling pathways. It is probably required for the amino acid-induced relocalization of mTORC1 to the lysosomes and its subsequent activation by the GTPase RHEB. This is a crucial step in the activation of the TOR signaling cascade by amino acids.
Images
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Immunohistochemistry of paraffin embedded mouse testis using Rrage (GB111319) at dilution of 1:2000 (300x lens) |
| Immunohistochemistry of paraffin embedded mouse kidney using Rrage (GB111319) at dilution of 1:2000 (400x lens) |
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Immunohistochemistry of paraffin embedded mouse lung using Rrage (GB111319) at dilution of 1:2000 (400x lens) |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed HeLa cells using RRAGC(GB111319) at dilution of 1:100-1:400 |
| Immunocytochemistry analysis of 4% paraformaldehyde-fixed NIH-3T3 cells using RRAGC(GB111319) at dilution of 1:100-1:400 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
