Reactivity: | M,R |
Applications: | WB |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Gene Name: | Protein CBFA2T1 |
Synonyms: | AML1T1, CBFA2T1, CDR, Cyclin D related protein, Eight twenty one protein, ETO, MTG8, MTG8b, Protein CBFA2T1 |
Immunogen: | Recombinant protein corresponding to Mouse RUNX1T1 |
Uniprot ID: | Q61909 |
Isotype: | IgG |
Purity: | Affinity purification |
Predicted MW. / Observed MW. | 64 kDa / 74 kDa |
Product Usage Information
WB | Mouse, Rat | 1: 300-1: 500 | brain |
Background
Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Can repress the expression of MMP7 in a ZBTB33-dependent manner. Can repress transactivation mediated by TCF12 (By similarity). Acts as a negative regulator of adipogenesis.
Images
Western blot analysis of RUNX1T1 (GB114460) at dilution of 1: 500 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |