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| Reactivity: | M,R |
| Applications: | IHC/IF |
| Host Species: | Mouse |
| Clonality: | Monoclonal |
| Gene Name: | DNA repair protein RAD51 homolog 1 |
Synonyms: | RAD51, BRCC5, FANCR, HHsRad51, HsT16930, MRMV2, RAD51A, RECA, RAD51 recombinase |
Immunogen: | Recombinant protein corresponding to Mouse Rad51 |
Uniprot ID: | Q08297 |
Isotype: | IgG1,κ |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Mouse, Rat | 1: 600-1: 1600 | brain |
Background
RAD51 is a eukaryotic gene, which is highly conserved from yeast to humans. The enzyme encoded by this gene is a member of the RAD51 protein family which assists in repair of DNA double strand breaks. In humans, RAD51 is a 339-amino acid protein that plays a major role in homologous recombination of DNA during double strand break repair. In this process, an ATP dependent DNA strand exchange takes place in which a template strand invades base-paired strands of homologous DNA molecules. RAD51 is involved in the search for homology and strand pairing stages of the process.
Images
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Immunohistochemistry of paraffin embedded mouse brain using RAD51 (GB12573) at dilution of 1: 800 (400x lens) |
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Immunohistochemistry of paraffin embedded rat brain using RAD51 (GB12573) at dilution of 1: 800 (400x lens) |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |