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| Reactivity: | H,M & H,M |
| Applications: | WB & ICC/IF |
| Host Species: | Rabbit |
| Clonality: | Polyclonal |
| Gene Name: | Transcription factor RelB |
Synonyms: | RELB, I-REL, IREL, REL-B, RELB proto-oncogene, NF-kB subunit |
Immunogen: | KLH conjugated Synthetic peptide corresponding to Mouse Rel B |
Uniprot ID: | Q04863 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Nucleus, Cytoplasm |
Product Usage Information
IHC/IF | Mouse, Rat | 1: 1000-1: 2000 | brain, colon, liver |
Background
NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity.
Images
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Immunohistochemistry analysis of paraffin-embedded mouse colon using Rel B (GB11353) at dilution of 1: 1000. |
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Immunohistochemistry analysis of paraffin-embedded mouse kidney using Rel B (GB11353) at dilution of 1: 1000. |
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Immunohistochemistry analysis of paraffin-embedded rat spleen using Rel B (GB11353) at dilution of 1: 1000. |
| Immunohistochemistry analysis of paraffin embedded mouse brain using RELB (GB11353) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse colon using RELB (GB11353) at dilution of 1: 1000 |
| Immunohistochemistry analysis of paraffin embedded mouse liver using RELB (GB11353) at dilution of 1: 1000 |
Storage
| Storage | Store at -20°C for one year. Avoid repeated freeze/ thaw cycles. |
| Storage Buffer | PBS with 0.02% sodium azide, 100 μg/ml BSA and 50% glycerol. |
