Reactivity: | H,M,R |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | S100 beta rabbit polyclonal antibody |
Gene Name: | Protein S100-B |
Synonyms: | NEF, S-100 protein beta chain, S-100 protein subunit beta, S100, S100 Beta, S100 calcium binding protein B, S100B, S100beta |
Immunogen: | Recombinant protein corresponding to Human S100 beta |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: | P04271 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
IHC/IF | Human, Mouse, Rat | 1: 500-1: 1000 | colon, glioblastoma multiforme, brain |
Background
Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling.
Images
Immunohistochemistry analysis of paraffin-embedded human colon using S100B (GB113884) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded mouse colon using S100B (GB113884) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded human glioblastoma multiforme using S100B (GB113884) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded mouse brain using S100B (GB113884) at dilution of 1: 1000 | |
Immunohistochemistry analysis of paraffin-embedded rat brain using S100B (GB113884) at dilution of 1: 1000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |