Reactivity: | H |
Applications: | IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | S100A12/CGRP rabbit polyclonal |
Gene Name: | Protein S100-A12 |
Synonyms: | CAAF1, CAGC, Calgranulin-C, CGRP, EN-RAGE, ENRAGE, MRP6, Neutrophil S100 protein, p6, S100A12 |
Immunogen: | Recombinant protein corresponding to Human S100A12/CGRP |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | |
Uniprot ID: |
Product Usage Information
Applications | Species | Dilution | Positive tissue |
IHC/IF | Human | 1: 2000-1: 4000 | colon cancer, squamous carcinoma of the cervix, spleen |
Background
S100A12 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. S100A12 is expressed abundantly in granulocytes, and has been implicated to play an important role on inflammatory reactions in various disease states.
Images
Immunohistochemistry analysis of paraffin-embedded human colon cancer using S100A12 (GB113483) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded human squamous carcinoma of the cervix using S100A12 (GB113483) at dilution of 1: 4000 | |
Immunohistochemistry analysis of paraffin-embedded human spleen using S100A12 (GB113483) at dilution of 1: 4000 |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |