Reactivity: | H,R & M,R |
Applications: | WB & IHC/IF |
Host Species: | Rabbit |
Clonality: | Polyclonal |
Full Name: | SCA2 rabbit polyclonal antibody |
Gene Name: | Ataxin-2 |
Synonyms: | Spinocerebellar ataxia type 2 protein homolog, Atxn2, Atx2, Sca2, Olivopontocerebellar ataxia 2, autosomal dominant, ASL13 |
Immunogen: | Recombinant protein corresponding to Mouse SCA2 |
Isotype: | IgG |
Purity: | Affinity purification |
Subcellular location: | Cytoplasm |
Predicted MW. | 136 kDa |
Observed MW. | 101 kDa |
Uniprot ID: | Q99700 |
Product Usage Information
Applications | Species | Dilution | Positive Sample |
WB | Human, Rat | 1: 2500-1: 5000 | liver |
IHC/IF | Mouse, Rat | 1: 300-1: 3000 | corpus striatum, hippocampus, prefrontal lobe, substantia nigra |
Background
Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.
Images
Western blot analysis of Ataxin2 (GB112402) at dilution of 1: 2500 | |
Immunofluorescence of paraffin embedded mouse hippocampus using Ataxin2 (GB112402) at dilution of 1: 300 (300x lens) | |
Immunofluorescence of paraffin embedded mouse prefrontal lobe using Ataxin2 (GB112402) at dilution of 1: 300 (450x lens) | |
Immunofluorescence of paraffin embedded rat corpus striatum using Ataxin2 (GB112402) at dilution of 1: 3000 (300x lens) | |
Immunofluorescence of paraffin embedded rat substantia nigra using Ataxin2 (GB112402) at dilution of 1: 300 (400x lens) |
Storage
Storage | Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Storage Buffer | PBS with 0.02%sodium azide,100 μg/ml BSA and 50% glycerol. |